The Department of Infectious Diseases at the NCGM is involved in many types of research projects, ranging from basic molecular microbiology to the development of diagnostic techniques to prevention and treatment of infectious diseases.

  1. Basic molecular microbiology
    1. Molecular and cellular mechanisms of TB
    2. Adherence of host cells to virulence factors in enterotoxigenic Escherichia coli
    3. Molecular mechanisms of severe invasive streptococcal infection
    4. Development of mouse models for disease analysis using developmental engineering techniques
  2. Epidemiological studies and development of new diagnostic techniques
    1. Mechanisms of resistance of multi-drug resistant Pseudomonas aeruginosa to antimicrobial agents
    2. Epidemiology of multidrug-resistant Mycobacterium tuberculosis
    3. Molecular epidemiology based on whole genome sequences in infectious diseases
    4. Development of rapid diagnostic kits for detection of highly pathogenic avian H5N1 influenza in humans
    5. Development of rapid diagnostic kits for multidrug-resistant Pseudomonas aeruginosa
    6. Development of vaccines against Shiga toxin-producing Escherichia coli (STEC) infections
  3. Prevention and treatment of infectious diseases
    1. Development of mice susceptible to human TB
    2. Development of oral vaccines for livestock against STEC infections using gene recombinant vegetables
    3. Screening of agents against multidrug-resistant Pseudomonas aeruginosa (Collaboration with Waseda University)
    4. Development of novel antimicrobial agents (Collaboration with the Institute of Medical Chemistry)