Our department aims at developing new methods for cell therapy using somatic stem cells, especially skin-derived cells. We are also interested in studying the mechanisms of various types of tissue development using embryonic stem (ES) cells or induced pluripotent stem (iPS) cells.

Stem cell research in the skin

  • Isolation and characterization of human/mouse adipose-derived stem cells and examination of their plasticity
  • Isolation and characterization of dermal multipotent stem cells and functional analyses in vivo
  • Analyses of hair inducing ability of dermal papilla cells

Research on ES cells and iPS cells

  • Development of inductive method of cardiomyocytes, pancreatic tissue.
  • Establishment of patient-derived iPS cells

Research on gene expression and transcription factors

  • Construction of a gene expression system which regulates multiple factors.
  • Functional analysis of Sox2 in various types of stem cells.