2003

221. Obinata, H., Yokomizo, T., Shimizu, T. and Izumi, T. (2003) Glucocorticoids up-regulate leukotriene B4 receptor-1 expression during neutrophilic differentiation of HL-60 cells. Biochem. Biophys. Res. Commun. 309, 114-119.

220. Okuno, T., Ago, H., Terawaki., K, Miyano, M., Shimizu, T. and Yokomizo, T. (2003) Helix 8 of the leukotriene B4 receptor is required for the conformational change to the low affinity state after G-protein activation. J. Biol. Chem. 278, 41500-41509.

219. Weijer, S., Leemans, J. C., Florquin, S., Shimizu, T., Ishii, S., and van der Poll, T. (2003) Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis. Immunology, 109, 552-556 .

218. Souza, D. G., Pinho, V., Soares, A. C. Shimizu, T., Ishii, S., and Teixeira, M. M. (2003) Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment. Brit. J. Pharmacol. 139, 733-740.

217. Yamauchi, T., Kamon, J., Ito, Y., Tsuchida, A., Yokomizo, T., Kita, S., Sugiyama, T., Miyagishi, M., Hara, K., Tsunoda, M., Murakami, K., Ohteki T., Uchida, S., Takenawa, S., Waki, H., Tsuno, N. H., Shibata, Y., Terauchi, Y., Froguel, P., Tobe, K., Koyasu, S., Taira, K., Kitamura, T., Shimizu, T., Nagai, R., and Kadowaki, T. (2003) Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423, 762-768.

216. Talvani, A., Santana, G., Barcelos, L. S., Ishii, S., Shimizu, T., Romanha, J., Silva, J. S., Soares, M. B. P. and Teixeira, M. M. (2003) Experimental Trypanosoma cruzi infection in platelet-activating factor-deficient mice. Microbes Infect. 5, 789-796.

215. Tokuoka, S. M., Ishii, S., Kawamura, N., Satoh, M., Shimada, A., Sasaki, S., Hirotsune, S., Wynshaw-Boris, A., and Shimizu, T. (2003) Involvement of Platelet-Activating Factor and LIS1 in Neuronal Migration. Eur. J. Neurosci. 18, 563-570.

214. Masuda, K., Itoh, H., Sakihama, T., Akiyama, C., Takahashi, K., Fukuda, R. Yokomizo, T., Shimizu, T., Kodama, T., and Hamakubo, T. (2003) A combinatorial G protein-coupled receptor reconstitution system on budded baculovirus: Evidence for Gαi and Gαo coupling to a human leukotriene B4 receptor. J. Biol. Chem. 278, 24552-24562.

213. Noguchi, K., Ishii, S., and Shimizu, T. (2003) Identification of p2y9/GPR23 as a Novel G Protein-Coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family J. Biol. Chem. 278, 25600-25606.

212. Hegen, M., Sun L., Uozumi N., Kume K., Goad, E. M., Nickerson-Nutter L. C., Shimizu T., and Clark D. J. (2003) Cytosolic Phospholipase A2α deficient Mice Are Resistant to Collagen-induced Arthritis J. Exp. Med. 197, 1297-1302.

211. Miyaura, C., Inada, M., Matsumoto, C., Ohshiba, C., Uozumi, N., Shimizu, T., and Ito, A. (2003) An Essential Role of Cytosolic Phospholipase A2α in Prostaglandin E2-mediated Bone Resorption Associated with Inflammation J. Exp. Med. 197, 1303-1310.

210. Omura, M., Sekine, H., Shimizu, T., Kataoka, H, and Touhara, K. (2003) In situ Ca imaging of odor responses in a coronal olfactory epithelium slice. Neuroreport 14, 1123-1127.

209. Asai, K, Hirabayashi, T, Houjou, T, Uozumi, N., Taguchi, R., and Shimizu, T. (2003) Human Group IVC phospholipase A2 (cPLA2γ): roles in the membrane remodeling and activation induced by oxidative stress. J. Biol. Chem. 278, 8909-8914.

208. Nagase T., Uozumi N., Aoki-Nagase T., Terawaki K., Ishii S., Tomita T., Yamamoto H., Hashizume K., Ouchi Y., and Shimizu T. (2003) A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice. Am. J. Physiol. Lung Cell Mol. Physiol. 284, L720-L726.

207. Usui, H., Taniguchi, M., Yokomizo, T., and Shimizu, T. (2003) Interaction of plexin A1 and plexin B1 at their cytoplamic domain. Biochem. Biophys. Res. Commun. 300, 927-931.

206. Taniguchi, M., Nagao, H., Takahashi Y. K., Yamaguchi, M., Mitsui, S., Yagi, T., Mori, K. and Shimizu, T. (2003) Distorted odor maps in the olfactory bulb of semaphorin 3A-deficient mice. J. Neurosci. 23, 1390-1397.

205. Vogensen, S. B., Stromgaard, K., Shindou, H., Jaracz, S., Suehiro, M., Ishii, S., Shimizu, T., and Nakanishi, K. (2003) Preparation of 7-substituted ginkgolide derivatives: potent platelet-activating factor (PAF) receptor antagonists. J. Med. Chem. 46, 601-608.