2016年（平成28年）

原著論文－英文

1. Tsukasaki M, Hamada K, Okamoto K, Nagashima K, Terashima A, Komatsu N, Win S, Okamura T, Nitta T, Yasuda H, Penninger JM, Takayanagi H.
   LOX fails to substitute for RANKL in osteoclastogenesis.
   J Bone and Mineral Res. 32(3): 434-439, 2017.
2. Tada T, Shrestha S, Shimada K, Ohara H, Sherchand JB, Pokhrel BM, Kirikae T.
   PER-8, a Novel extended-spectrum β-lactamase PER variant, from an Acinetobacter baumannii clinical isolate in Nepal.
   Antimicrob Agents Chemother. 23:61(3), 2017.
3. Ogura K, Terasaki Y, Miyoshi-Akiyama T, Terasaki M, Moss J, Noda M, Yahiro K.
   Vibrio cholerae Cholix toxin-induced HepG2 cell death is enhanced by tumor necrosis factor-alpha through ROS and intracellular signal-regulated kinases.
   Toxicol Sci. 156(2):455-468, Jan 13, 2017.
4. Sato T, Hamabata T, Takita E, Matsui T, Sawada T, Imaoka T, Nakanishi N, Nakayama K, Tsukahara T.
   Improved porcine model for Shiga toxin-producing Escherichia coli infection by deprivation of colostrum feeding in newborn piglets.
   Animal Sci J. 88:826-831, 2017.
5. Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.
   The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.
   Sci Signal. 10(460), Jan 3, 2017.
6. Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W.
   Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.
   Sci Signal. 10(466), Feb 14, 2017.
7. Takahashi E, Unoki-Kubota H, Shimizu Y, Okamura T, Iwata W, Kajio H, Yamamoto-Honda R, Shiga T, Yamashita S, Tobe K, Okumura A, Matsumoto M, Yasuda K, Noda M, Kaburagi Y.
   Proteomic analysis of serum biomarkers for pre-diabetes using the Long-Event Agouti rat, a spontaneous animal model of type 2 diabetes mellitus.
   J Diabetes Investig. Feb 2, 2017. [Epub ahead of print].
8. Suzuki-Yamazaki N, Yanobu-Takanashi R, Okamura T, Takaki S.
   IL-10 production in murine IgM+ CD138hi cells is driven by Blimp-1 and downregulated in class-switched cells.
   Eur J Immunol. (3):493-503, 2017.
9. Miyoshi-Akiyama T, Sherchan JB, Doi Y, Nagamatsu M, Sherchand JB, Tandukar S, Ohmagari N, Kirikae T, Ohara H, Hayakawa K.
   Comparative genome analysis of extended-spectrum-β-lactamase-producing Escherichia coli sequence type 131 strains from Nepal and Japan.
   mSphere. 1(5). Oct 26, 2016.
10. Matsumura K, Iwai H, Kato-Miyazawa M, Kirikae F, Zhao J, Yanagawa T, Ishii T, Miyoshi-Akiyama T, Funatogawa K, Kirikae T.
    Peroxiredoxin 1 contributes to host defenses against Mycobacterium tuberculosis.
    J Immunol. 197(8):3233-3244, 2016.
11. Hayakawa K, Mezaki K, Sugiki Y, Nagamatsu M, Miyoshi-Akiyama T, Kirikae T, Kutsuna S, Takeshita N, Yamamoto K, Katanami Y, Ohmagari N.
    High rate of multidrug-resistant organism colonization among patients hospitalized overseas highlights the need for preemptive infection control.
    Am J Infect Control. 44(11):e257-e259, 2016.
12. Ishikura S, Tsunoda T, Nakabayashi K, Doi K, Koyanagi M, Hayashi K, Kawai T, Tanaka Y, Iwaihara Y, Luo H, Nishi K, Okamura T, Shirasawa S.
    Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.
    Biochim Biophys Acta. 1859(11):1398-1410, 2016.
13. Tada T, Nhung PH, Miyoshi-Akiyama T, Shimada K, Tsuchiya M, Phuong DM, Anh NQ, Ohmagari N, Kirikae T.
    Multidrug-resistant ST235 Pseudomonas aeruginosa clinical isolates producing IMP-26 with increased carbapenem hydrolyzing activities in Vietnam.
    Antimicrob Agents Chemother. 60(11):6853-6858, 2016.
14. Watanabe S, Matsumura K, Iwai H, Funatogawa K, Haishima Y, Fukui C, Okumura K, Kato-Miyazawa M, Hashimoto M, Teramoto K, Kirikae F, Miyoshi-Akiyama T, Kirikae T.
    A mutation in the 16S rRNA decoding region attenuates the virulence of Mycobacterium tuberculosis.
    Infect Immun. 84:2264-2273, 2016.
15. Kawamura Y, Tomida J, Miyoshi-Akiyama T, Okamoto T, Narita M, Hashimoto K, Cnockaert M, Vandamme P, Morita Y, Sawa T, Akaike T.
    Proposal of Helicobacter canicola sp. nov., previously identified as Helicobacter cinaedi, isolated from canines.
    Syst Appl Microbiol. 39(5):307-312, 2016.
16. Shrestha S, Tada T, Shrestha B, Kirikae T, Ohara H, Rijal BP, Pokhrel BM, Sherchand JB.
    Emergence of aminoglycoside resistance due to armA methylase in multi-drug resistant Acinetobacter Baumannii isolates in a university hospital in Nepal.
    J Nepal Health Res Counc. 14(33):72-76, 2016.
17. Sugiyama K, Sasano T, Kurokawa J, Takahashi K, Okamura T, Kato N, Isobe M, Furukawa T.
    Oxidative stress induced ventricular arrhythmia andi mpairment of cardiac function in Nos1ap deleted mice.
    Int Heart J 57(3):341- 349, 2016.
18. Tada T, Miyoshi-Akiyama T, Shimada K, Shiroma A, Nakano K, Teruya K, Satou K, Hirano T, Shimojima M, Kirikae T.
    A carbapenem-rresistant Pseudomonas aeruginosa isolate harboring two copies of blaIMP-34 encoding a metallo-β-lactamase.
    PLoS One. 11(4):e0149385, 2016.
19. Matono T, Hayakawa K, Hirai R, Tanimura A, Yamamoto K, Fujiya Y, Mawatari M, Kutsuna S, Takeshita N, Mezaki K, Ohmagari N, Miyoshi-Akiyama T.
    Emergence of a daptomycin-non-susceptible Enterococcus faecium strain that encodes mutations in DNA repair genes after high-dose daptomycin therapy.
    BMC Res Notes. 9:197, 2016.
20. Marusugi K, Nakano K, Sasaki H, Kimura J, Yanobu-Takanashi R, Okamura T, Sasaki N.
    Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing.
    J Vet Med Sci. 78, 1413-1420, 2016.
21. Ishikura S, Iwaihara Y, Tanaka Y, Luo H, Nishi K, Doi K, Koyanagi M, Okamura T, Tsunoda T, Shirasawa S.
    The nuclear zinc finger protein Zfat maintains FoxO1 proteinlevels in peripheral T cells by regulating the activities of autophagy and the Akt signaling pathway.
    J Biol Chem. 291:15282-15291, 2016.
22. Sabui S, Debnath A, Ghosal A, Wajima T, Hamabata T, Ramamurthy T, Ghosh AN, Basak S, Chatterjee NS.
    Characterization of oligomeric assembly of colonization factor CS6 from enterotoxigenic Escherichia coli.
    Microbiology. 162:72-83, 2016.
23. Debnath A, Sabui S, Wajima T, Hamabata T, Baberjee R, Ramamurthy T, Chatterjee NS.
    Functional role of N- and C-terminal amino acids in the structural subunits of colonization factor CS6 expressed by enterotoxigenic Escherichia coli.
    J Bacteriol. 198:1429-1441, 2016.

原著論文－和文

口頭・ポスター発表－国際学会・研究会

1. Iwai H, Matsumura K, Kirikae F, Cox JS, Funatogawa K, Miyoshi-Akiyama T, Kirikae T.
   A mycobacterial virulence protein, PE_PGRS62, inhibits autophagy in macrophages.
   The 24th International symposium on molecular cell biology of macrophages. Jun 4, 2016, Tokyo, Japan.
2. Ogura K, Watanabe S, Kirikae T, Miyoshi-Akiyama T.
   Complete genome sequence of a Streptococcus pyogenes emm3 Strain, M3-b, isolated from a japanese patient with Streptococcal toxic shock syndrome case, and comparative genomics of S. pyogenes emm3 Strains.
   ASM microb 2016, Jun 16-20, 2016, Boston, USA.
3. Watanabe S, Matsumura K, Iwai H, Funatogawa K, Haishima Y, Fukui C, Okumura K, Kato-Miyazawa M, Hashimoto M, Teramoto K, Kirikae F, Miyoshi-Akiyama T, Kirikae T.
   A mutation in the 16S rRNA decoding region attenuates the virulence of Mycobacterium tuberculosis.
   Keystone Symposia, Jan 14-18, 2017, Vancouver, Canada.

口頭・ポスター発表－国内学会・研究会

1. 清水 有紀子, 大熊 喜彰, 岡村 匡史.
   LC/MS/MSによる白血球中のシスチン定量法.
   第63回日本実験動物学会総会. 川崎, 5月, 2016.
2. 中野 堅太, 高梨 理絵子, 清水 有紀子, 金子 武人, 岡村 匡史.
   電気穿孔法を用いた効率的マウスゲノム編集法.
   第63回日本実験動物学会総会. 川崎, 5月, 2016.
3. 竹本 訓彦, 渡邊 真弥, 秋山 徹.
   A群溶血性レンサ球菌(Streptococcus pyogenes)における新規病原性（制御）因子の探索.
   第10回日本ゲノム微生物学会. 若手の会研究会, 9月, 東京, 2016.
4. 清水 有紀子, 高梨 理絵子, 中野 堅太, 大熊 喜彰, 岡村 匡史.
   シスチノーシスモデルラットを用いた白血球中シスチン測定法の確立.
   第159回日本獣医学会学術集会. 9月, 藤沢, 2016.
5. 丸杉 貴世馬, 中野 堅太, 金田 理穂, 佐々木 隼人, 矢延-高梨 理絵子, 岡村 匡史, 佐々木 宣哉.
   Tensin2の各ドメイン変異マウスを用いた腎症発症機序解明への試み.
   第159回日本獣医学会学術集会. 9月, 藤沢, 2016.
6. 中野 堅太, 高梨 理絵子, 新井 哲也, 岡村 匡史.
   エレクトロポレーション法による汎用的電気条件の検討.
   第159回日本獣医学会学術集会. 9月, 藤沢, 2016.
7. 清水 有紀子, 大熊 喜彰, 岡村 匡史, 七野 浩之.
   シスチノーシスの確定診断に用いるシスチン分析法の確立.
   第58回日本先天代謝異常学会/第14回アジア先天代謝異常シンポジウム. 10月, 東京, 2016.
8. 松村 和典, 祝 弘樹, 加藤-宮沢 雅子, 切替 富美子, 趙 吉子, 柳川 徹, 石井 哲郎, 舩渡川 圭次, 秋山 徹, 切替 照雄.
   Analysis of PRDX1 which contributes to host defenses against Mycobacterium tuberculosis.
   第90回日本細菌学会総会. 3月, 仙台, 2017.
9. 渡邊 真弥, 松村 和典, 祝 弘樹, 舩渡川 圭次, 加藤 雅子, 切替 富美子, 秋山 徹, 崔 龍珠, 切替 照雄.
   カナマイシン耐性に寄与する16SリボゾームRNAの解読領域の変異と結核菌の弱毒化.
   第90回日本細菌学会総会. 3月, 仙台, 2017.
10. 竹本 訓彦, 渡邊 真弥, 秋山 徹.
    A群溶血性連鎖球菌（Streptococcus pyrogenes）における新規病原性（制御）因子の探索.
    第90回日本細菌学会総会. 3月, 仙台, 2017.
11. Ogura K, Miyoshi-Akiyama T.
    Studies on relationship between Streptococcus dysgalactiae subsp. equisimilis infection and diabetes mellitus.
    第90回日本細菌学会総会. 3月, 仙台, 2017.
12. Tada T, Miyoshi-Akiyama T, Ohmagari N, Kirikae T.
    Molecular epidemiology of multidrug-resistant Pseudomonas aeruginosa in a medical setting in Vietnam.
    第90回日本細菌学会総会. 3月, 仙台, 2017.
13. 松村 和典, 祝 弘樹, 加藤-宮沢 雅子, 切替 富美子, 趙 吉子, 柳川 徹, 石井 哲郎, 舩渡川 圭次, 秋山 徹, 切替 照雄.
    結核菌に寄与する宿主タンパク質PRDX1の機能解析.
    第87回実験結核研究会. 3月, 東京, 2017.

著書・総説

その他