Publications

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Publications

・Sato K, Misawa N, Iwami S, Satou Y, Matsuika M, Ishizaka Y, Ito M, Aihara K, An D-S, Koyanagi Y. HIV-1 Vpr accelerates viral replication during acute infection by exploiting proliferating CD4+ T cells in vivo. PloS Pathogen, in press.

・Matsunaga A, Hishima T, Tanaka N, Yamazak M, Mochizuki M, Tanuma J, Oka S, Ishizaka Y, Shimura M and Hagiwara S. DNA methylation profiling can classify HIV-associated lymphomas. AIDS, in press.

・Iijima K, Okudaira N, Tamura M, Saito Y, Shimura M, Goto M, Matsunaga A, Hoshino S, Kano S, Hagiwara S, Tanuma J, Gatanaga H, Baba M, Iguchi T, Yanagita M, Oka S, Okamura T and Ishizaka Y. Retrotransposition of long interspersed element-1 in the kidney by human immunodeficiency virus type-1 Vpr. Retrovirology, 10:83, 2013.

・Richard J, Pham TN, Ishizaka Y, Cohen EA. Viral protein R upregulates expression of ULBP2 on unifected bystander cells during HIV-1 infection of CD4+ T lymphocytes. Virology 443:248-56, 2013.

・Matsuyama S, Matsunaga A, Sakamoto S, Iida Y, Suzuki Y, Ishizaka Y, Yamauchi K, Ishikawa T, Shimura M. Metallomics. Scanning protein analysis of electrofocusing gels using X-ray fluorescence. Metallomics 5: 492-500, 2013 (DOI: 10.1039/C3MT20266F).

・Koyama T, Sun B, Tokunaga K, Tatsumi M and Ishizaka Y. DNA damage aids human immunodeficiency virus type 1 infection by overcoming integrase inhibition. Retrovirology 10:21, 2013.

・Masaya Fukushi, Yoshiyuki Yoshinaka, Yusuke Matsuoka, Seisuke Hatakeyama, Yukihito Ishizaka, Teruo Kirikae, Takehiko Sasazuki, Tohru Miyoshi-Akiyama. Monitoring S protein maturation in the endoplasmic reticulum by calnexin is important for the infectivity of severe acute respiratory syndrome-coronavirus. J. Virol. 86(21):11745-53, 2012 Nov;

・Noriyuki Okudaira, Tadashi Okamura, Masato Tamura, Kenta Iijma, Motohito Goto, Akihiro Matsunaga, Masako Ochiai, Hitoshi Nakagama, Shigeyuki Kano, Yoshiaki Fujii-Kuriyama and Yukihito Ishizaka. Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor. Oncogene, in press

・Koyama T, Shimura M, Minemoto Y, Nohara S, Shibata S, Iida Y, Iwashita S, Hasegawa M, Kurabayashi T, Hamada H, Kono K, Honda E, Aoki I, Ishizaka Y. Evaluation of selective tumor detection by clinical magnetic resonance imaging using antibody-conjugated superparamagnetic iron oxide J. Cotrol. Release, 159: 413-8, 2012.

・Okudaira N, Goto M, Abe Y, Tamura M, An Y, Kano S, Ishizaka Y, Okamura T. Involvement of retrotransposition of long interspersed nucleotide element-1 in DMBA/TPA-induced skin carcinogenesis. Cancer Sci. 102 (11): 2000-2006, 2011.

・Shimura M, Toyoda Y, Iijima K, Kinomoto M, Tokunaga K,Yoda K, Yanagida M, Sata T and Ishizaka Y. Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation. J. Cell. Biol, 194: 721-35, 2011. Commentary in J. Cell. Biol 11/08/30.

・Uchida S, Watanabe N, Kudo Y, Yoshioka K, Matsunaga T, Ishizaka Y, Nakagama H, Poon RYC, and Yamashita K. SCFβTrCP mediates stress-activated MAP kinase-induced Cdc25B degradation. J. Cell Sci. 124:2816-2825, 2011.

・Kono K, Nakashima S, Kokuryo D, Aoki I, Shimomoto H, Aoshima S, Maruyama K, Yuba E, Kojima C, Harada A, Ishizaka Y. Multifunctional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy. Biomaterials 32: 1387-1395, 2011

Publications

・奥平准之、石坂幸人. 難病発症に関わる内在性レトロエレメントの活性化とその機構. 日本生化学会誌、84, 870-874, 2012

・Ishizaka Y, Okudaira N, Tamura M, Iijima K, Shimura M, Goto M, Okamura T. Modes of retrotransposition of long interspersed element-1 by environmental factors. Front Microbiol. 3:191, 2012. Epub 2012 May 31.

・Ishizaka Y, Okudaira N, Okamura T. 2012 Regulation of retrotransposition of long interspersed element-1 by mitogen-activated protein kinases. pp 187-198. In Gabriela Da Silva Xavier (ed), Protein Kinases / Book 1, InTech - Open Access Publisher, Croatia. http://www.intechopen.com/books/protein-kinases

ResearchProject
  • Integration of HIV-1 at DNA double strands break site
  • Mode of respiratory distress by SARS-CoV
  • Autoantibodies in patients of collagen diseases
  • Novel peptide vector developed at NCGM
  • Retrotransposition of endogenous retroelements
  • Visualization of intracellular elements