業績
■論文
《2024年》
- Wang L, Koui Y, Kanegae K, Kido T, Tamura-Nakano M, Yabe S, Tai K, Nakajima Y, Kusuhara H, Sakai Y, Miyajima A, Okochi H, Tanaka M. Establishment of human induced pluripotent stem cell-derived hepatobiliary organoid with bile duct for pharmaceutical research use. Biomaterials. 2024 Oct;310:122621. doi: 10.1016/j.biomaterials.2024.122621. Epub 2024 May 22. PubMed PMID: 38815455.
- Tang C, Tamura-Nakano M, Kobayakawa K, Ozawa T, Onojima T, Kajitani R, Itoh T, Tachibana K. A single gene determines allorecognition in hydrozoan jellyfish Cladonema radiatum inbred lines. J Exp Zool A Ecol Integr Physiol. 2024 Jul 8;. doi: 10.1002/jez.2853. [Epub ahead of print] PubMed PMID: 38973306.
- Katagiri D, Tsukada A, Izumi S, Shimizu Y, Terada-Hirashima J, Uemura Y, Kusaba Y, Takasaki J, Takoi H, Tamura-Nakano M, Hojo M, Takano H, Noiri E, Abe S, Azuma A, Sugiyama H. Blood perfusion with polymyxin B immobilized columns in patients with COVID-19 requiring oxygen therapy. Sci Rep. 2024 May 31;14(1):12550. doi: 10.1038/s41598-024-63330-2. PubMed PMID: 38822071; PubMed Central PMCID: PMC11143350.
- Awazawa M, Matsushita M, Nomura I, Kobayashi N, Tamura-Nakano M, Sorimachi Y, Takubo K, Ueki K. Imeglimin improves systemic metabolism by targeting brown adipose tissue and gut microbiota in obese model mice. Metabolism. 2024 Apr;153:155796. doi: 10.1016/j.metabol.2024.155796. Epub 2024 Jan 21. PubMed PMID: 38262576.
《2023年》
- Tsutsui Y, Mori T, Yoshio S, Sato M, Sakata T, Yoshida Y, Kawai H, Yoshikawa S, Yamazoe T, Matsuda M, Kakazu E, Osawa Y, Oyama C, Tamura-Nakano M, Kawaguchi T, Yoshizumi T, Kanto T. Exercise changes the intrahepatic immune cell profile and inhibits the progression of nonalcoholic steatohepatitis in a mouse model. Hepatol Commun. 2023 Oct 1;7(10). doi: 10.1097/HC9.0000000000000236. eCollection 2023 Oct 1. PubMed PMID: 37756046; PubMed Central PMCID: PMC10531194.
- Okumura W, Tadahira K, Kozono T, Tamura-Nakano M, Sato H, Matsui H, Dohi T, Rohrer J, Tonozuka T, Nishikawa A. Jaw1/LRMP is associated with the maintenance of Golgi ribbon structure. J Biochem. 2023 Apr 26;173(5):383-392. doi: 10.1093/jb/mvad004. PubMed PMID: 36689741.
《2022年》
- Higashi-Kuwata N, Yabe SG, Fukuda S, Nishida J, Tamura-Nakano M, Hattori SI, Okochi H, Mitsuya H.
Generation of Angiotensin-Converting Enzyme 2/Transmembrane Protease Serine 2-Double-Positive Human Induced Pluripotent Stem Cell-Derived Spheroids for Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Drug Evaluation.
Microbiol Spectr. 2022 Dec 21;10(6):e0349022. doi: 10.1128/spectrum.03490-22. Epub 2022 Oct 31. PubMed PMID: 36314907; PubMed Central PMCID: PMC9769601.
- Sasako T, Umehara T, Soeda K, Kaneko K, Suzuki M, Kobayashi N, Okazaki Y, Tamura-Nakano M, Chiba T, Accili D, Kahn CR, Noda T, Asahara H, Yamauchi T, Kadowaki T, Ueki K.
Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.
Nat Commun. 2022 Oct 5;13(1):5655. doi: 10.1038/s41467-022-33008-2. PubMed PMID: 36198696; PubMed Central PMCID: PMC9535008.
- Kawai H, Osawa Y, Matsuda M, Tsunoda T, Yanagida K, Hishikawa D, Okawara M, Sakamoto Y, Shimagaki T, Tsutsui Y, Yoshida Y, Yoshikawa S, Hashi K, Doi H, Mori T, Yamazoe T, Yoshio S, Sugiyama M, Okuzaki D, Komatsu H, Inui A, Tamura-Nakano M, Oyama C, Shindou H, Kusano H, Kage M, Ikegami T, Yanaga K, Kanto T.
Sphingosine-1-phosphate promotes tumor development and liver fibrosis in mouse model of congestive hepatopathy.
Hepatology. 2022 Jul;76(1):112-125. doi: 10.1002/hep.32256. Epub 2021 Dec 22. PubMed PMID: 34855990.
- Matsushita M, Awazawa M, Kobayashi N, Ikushima YM, Soeda K, Tamura-Nakano M, Muratani M, Kobayashi K, Bluher M, Bruning JC, Ueki K.
An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
Cell Chem Biol. 2022 Apr 21;29(4):680-689.e6. doi: 10.1016/j.chembiol.2021.12.008. Epub 2022 Jan 4. PubMed PMID: 34986326.
- Kozono T*, Tamura-Nakano M*, Kawamura YI, Tonozuka T, Nishikawa A.
Novel protocol to observe the intestinal tuft cell using transmission electron microscopy.
Biol Open. 2022 Feb 15;11(2). doi: 10.1242/bio.059007. Epub 2022 Feb 16. PubMed PMID: 34994390; PubMed Central PMCID: PMC8864298.
*Both authors contributed equally to this work.
《2021年》
- Tateno H, Tamura-Nakano M, Kusakabe H, Hirohashi N, Kawano N, Yanagimachi R.
Sperm acrosome status before and during fertilization in the Chinese hamster (Cricetulus griseus), and observation of oviductal vesicles and globules.
Mol Reprod Dev. 2021 Dec;88(12):793-804. doi: 10.1002/mrd.23547. Epub 2021 Nov 29. PubMed PMID: 34845795.
- Shinohara K, Chujo D, Tamura-Nakano M, Kurokawa T, Matsumoto S, Shimoda M.
High-quality porcine islets isolated from aged miniature pigs.
Xenotransplantation. 2021 May;28(3):e12675. doi: 10.1111/xen.12675. Epub 2021 Feb 5. PubMed PMID: 33543796.
- Kozono T, Sato H, Okumura W, Jogano C, Tamura-Nakano M, Kawamura YI, Rohrer J, Tonozuka T, Nishikawa A.
The N-terminal region of Jaw1 has a role to inhibit the formation of organized smooth endoplasmic reticulum as an intrinsically disordered region.
Sci Rep. 2021 Jan 12;11(1):753. doi: 10.1038/s41598-020-80258-5. PubMed PMID: 33436890; PubMed Central PMCID: PMC7804115.
《2020年》
- Okubo N, Tamura-Nakano M, Watanabe T.
Experimental observation of microplastics invading the endoderm of anthozoan polyps.
Mar Environ Res. 2020 Dec;162:105125. doi: 10.1016/j.marenvres.2020.105125. Epub 2020 Aug 28. PubMed PMID: 32919228.
- Eto M, Shindou H, Yamamoto S, Tamura-Nakano M, Shimizu T.
Lysophosphatidylethanolamine acyltransferase 2 (LPEAT2) incorporates DHA into phospholipids and has possible functions for fatty acid-induced cell death.
Biochem Biophys Res Commun. 2020 May 21;526(1):246-252. doi: 10.1016/j.bbrc.2020.03.074. Epub 2020 Mar 21. PubMed PMID: 32204912.
- Kudo M, Ishiura N, Tamura-Nakano M, Shimizu T, Kamata M, Akasaka E, Nakano H, Okuma Y, Tada Y, Okochi H, Tamaki T.
Abnormal keratinization and cutaneous inflammation in Mal de Meleda.
J Dermatol. 2020 May;47(5):554-558. doi: 10.1111/1346-8138.15296. Epub 2020 Mar 10. PubMed PMID: 32157724.
- Hirose M, Honda A, Fulka H, Tamura-Nakano M, Matoba S, Tomishima T, Mochida K, Hasegawa A, Nagashima K, Inoue K, Ohtsuka M, Baba T, Yanagimachi R, Ogura A.
Acrosin is essential for sperm penetration through the zona pellucida in hamsters.
Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2513-2518. doi: 10.1073/pnas.1917595117. Epub 2020 Jan 21. PubMed PMID: 31964830; PubMed Central PMCID: PMC7007544.
《2019年》
- Nagai M, Noguchi R, Takahashi D, Morikawa T, Koshida K, Komiyama S, Ishihara N, Yamada T, Kawamura YI, Muroi K, Hattori K, Kobayashi N, Fujimura Y, Hirota M, Matsumoto R, Aoki R, Tamura-Nakano M, Sugiyama M, Katakai T, Sato S, Takubo K, Dohi T, Hase K.
Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses.
Cell. 2019 Aug 22;178(5):1072-1087.e14. doi: 10.1016/j.cell.2019.07.047. PubMed PMID: 31442401.
- Tamehiro N, Nishida K, Sugita Y, Hayakawa K, Oda H, Nitta T, Nakano M, Nishioka A, Yanobu-Takanashi R, Goto M, Okamura T, Adachi R, Kondo K, Morita A, Suzuki H.
Ras homolog gene family H (RhoH) deficiency induces psoriasis-like chronic dermatitis by promoting T(H)17 cell polarization.
J Allergy Clin Immunol. 2019 May;143(5):1878-1891. doi: 10.1016/j.jaci.2018.09.032. Epub 2018 Oct 17. PubMed PMID: 30339851.
- Ishiura N, Tamura-Nakano M, Okochi H, Tateishi C, Maki M, Shimoda Y, Ishii N, Hashimoto T, Tamaki T.
Herpetiform pemphigus with characteristic transmission electron microscopic findings of various-sized ballooning vacuoles in keratinocytes without acantholysis.
Br J Dermatol. 2019 Jan;180(1):187-192. doi: 10.1111/bjd.16554. Epub 2018 Jun 20. PubMed PMID: 29573413.
《2018年》
- Kozono T, Tadahira K, Okumura W, Itai N, Tamura-Nakano M, Dohi T, Tonozuka T, Nishikawa A.
Jaw1/LRMP has a role in maintaining nuclear shape via interaction with SUN proteins.
J Biochem. 2018 Oct 1;164(4):303-311. doi: 10.1093/jb/mvy053. PubMed PMID: 29878215.
- Watanabe-Takahashi M, Yamasaki S, Murata M, Kano F, Motoyama J, Yamate J, Omi J, Sato W, Ukai H, Shimasaki K, Ikegawa M, Tamura-Nakano M, Yanoshita R, Nishino Y, Miyazawa A, Natori Y, Toyama-Sorimachi N, Nishikawa K. >
Exosome-associated Shiga toxin 2 is released from cells and causes severe toxicity in mice.
Sci Rep. 2018 Jul 17;8(1):10776. doi: 10.1038/s41598-018-29128-9. PubMed PMID: 30018364; PubMed Central PMCID: PMC6050230.
- Shiba D, Terayama M, Yamada K, Hagiwara T, Oyama C, Tamura-Nakano M, Igari T, Yokoi C, Soma D, Nohara K, Yamashita S, Dohi T, Kawamura YI.
Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.
Medicine (Baltimore). 2018 Apr;97(15):e0357. doi: 10.1097/MD.0000000000010357. PubMed PMID: 29642180; PubMed Central PMCID: PMC5908574.
- Hashimoto M, Matsumoto T, Tamura-Nakano M, Ozono M, Hashiguchi S, Suda Y.
Characterization of outer membrane vesicles of Acetobacter pasteurianus NBRC3283.
J Biosci Bioeng. 2018 Apr;125(4):425-431. doi: 10.1016/j.jbiosc.2017.11.006. Epub 2017 Dec 6. PubMed PMID: 29208444.
《2017年》
- Hirata Y, Sezaki T, Tamura-Nakano M, Oyama C, Hagiwara T, Ishikawa T, Fukuda S, Yamada K, Higuchi K, Dohi T, Kawamura YI.
Fatty acids in a high-fat diet potentially induce gastric parietal-cell damage and metaplasia in mice.
J Gastroenterol. 2017 Aug;52(8):889-903. doi: 10.1007/s00535-016-1291-0. Epub 2016 Nov 21. PubMed PMID: 27873093.
- Satake T, Yamashita K, Hayashi K, Miyatake S, Tamura-Nakano M, Doi H, Furuta Y, Shioi G, Miura E, Takeo YH, Yoshida K, Yahikozawa H, Matsumoto N, Yuzaki M, Suzuki A.
MTCL1 plays an essential role in maintaining Purkinje neuron axon initial segment.
EMBO J. 2017 May 2;36(9):1227-1242. doi: 10.15252/embj.201695630. Epub 2017 Mar 10. PubMed PMID: 28283581; PubMed Central PMCID: PMC5412768.
《2016年》
- Sezaki T, Hirata Y, Hagiwara T, Kawamura YI, Okamura T, Takanashi R, Nakano K, Tamura-Nakano M, Burkly LC, Dohi T.
Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice.
2017 Apr 7;23(13):2294-2307. doi: 10.3748/wjg.v23.i13.2294. PubMed PMID: 28428709; PubMed Central PMCID: PMC5385396.
- Hirohashi N*, Tamura-Nakano M*, Nakaya F, Iida T, Iwata Y.
Sneaker Male Squid Produce Long-lived Spermatozoa by Modulating Their Energy Metabolism.
J Biol Chem. 2016 Sep 9;291(37):19324-34. doi: 10.1074/jbc.M116.737494. Epub 2016 Jul 6. PubMed PMID: 27385589; PubMed Central PMCID: PMC5016673.
*Both authors contributed equally to this work.
- Hino T, Muro Y, Tamura-Nakano M, Okabe M, Tateno H, Yanagimachi R.
The Behavior and Acrosomal Status of Mouse Spermatozoa In Vitro, and Within the Oviduct During Fertilization after Natural Mating.
Biol Reprod. 2016 Sep;95(3):50. doi: 10.1095/biolreprod.116.140400. Epub 2016 Jul 14. PubMed PMID: 27417908.
《2015年》
- Hashidate-Yoshida T, Harayama T, Hishikawa D, Morimoto R, Hamano F, Tokuoka SM, Eto M, Tamura-Nakano M, Yanobu-Takanashi R, Mukumoto Y, Kiyonari H, Okamura T, Kita Y, Shindou H, Shimizu T.
Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport.
Elife. 2015 Apr 21;4. doi: 10.7554/eLife.06328. PubMed PMID: 25898003; PubMed Central PMCID: PMC4436788.
- Otsubo T, Hagiwara T, Tamura-Nakano M, Sezaki T, Miyake O, Hinohara C, Shimizu T, Yamada K, Dohi T, Kawamura YI.
Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma.
Cancer Med. 2015 Mar;4(3):415-25. doi: 10.1002/cam4.369. Epub 2015 Jan 12. PubMed PMID: 25583674; PubMed Central PMCID: PMC4380967.
《2014年》
- Yoshida MA, Yamada L, Ochi H, Iwata Y, Tamura-Nakano M, Sawada H, Sauer WH, Ogura A, Hirohashi N.
Integrative omics analysis reveals differentially distributed proteins in dimorphic euspermatozoa of the squid, Loligo bleekeri.
Biochem Biophys Res Commun. 2014 Aug 1;450(3):1218-24. doi: 10.1016/j.bbrc.2014.04.076. Epub 2014 Apr 24. PubMed PMID: 24768636.
- Kimura T, Hamazaki TS, Sugaya M, Fukuda S, Chan T, Tamura-Nakano M, Sato S, Okochi H.
Cilostazol improves lymphatic function by inducing proliferation and stabilization of lymphatic endothelial cells.
J Dermatol Sci. 2014 May;74(2):150-8. doi: 10.1016/j.jdermsci.2014.01.001. Epub 2014 Jan 21. PubMed PMID: 24517869.
《2013年》
- Hikichi T, Matoba R, Ikeda T, Watanabe A, Yamamoto T, Yoshitake S, Tamura-Nakano M, Kimura T, Kamon M, Shimura M, Kawakami K, Okuda A, Okochi H, Inoue T, Suzuki A, Masui S.
Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles.
Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6412-7. doi: 10.1073/pnas.1220200110. Epub 2013 Apr 2. PubMed PMID: 23550161; PubMed Central PMCID: PMC3631636.
■書籍・メディア等
■謝辞掲載分
《2023年》
- Takashina T, Matsunaga A, Shimizu Y, Sakuma T, Okamura T, Matsuoka K, Yamamoto T, Ishizaka Y.
Robust protein-based engineering of hepatocyte-like cells from human mesenchymal stem cells.
Hepatol Commun. 2023 Mar 1;7(3):e0051. doi: 10.1097/HC9.0000000000000051. eCollection 2023 Mar 1. PubMed PMID: 36848084; PubMed Central PMCID: PMC9974069.
- Soeda K, Sasako T, Enooku K, Kubota N, Kobayashi N, Ikushima YM, Awazawa M, Bouchi R, Toda G, Yamada T, Nakatsuka T, Tateishi R, Kakiuchi M, Yamamoto S, Tatsuno K, Atarashi K, Suda W, Honda K, Aburatani H, Yamauchi T, Fujishiro M, Noda T, Koike K, Kadowaki T, Ueki K.
Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Nat Commun. 2023 Oct 18;14(1):6584. doi: 10.1038/s41467-023-42334-y. PubMed PMID: 37852976; PubMed Central PMCID: PMC10584811.
《2016年》
《2014年》
- Kobayashi T, Shimabukuro-Demoto S, Yoshida-Sugitani R, Furuyama-Tanaka K, Karyu H, Sugiura Y, Shimizu Y, Hosaka T, Goto M, Kato N, Okamura T, Suematsu M, Yokoyama S, Toyama-Sorimachi N.
The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production.
Immunity. 2014 Sep 18;41(3):375-388. doi: 10.1016/j.immuni.2014.08.011. PubMed PMID: 25238095.
- Eto K, Nishimura W, Oishi H, Udagawa H, Kawaguchi M, Hiramoto M, Fujiwara T, Takahashi S, Yasuda K.
MafA is required for postnatal proliferation of pancreatic β-cells.
PLoS One. 2014;9(8):e104184. doi: 10.1371/journal.pone.0104184. eCollection 2014. PubMed PMID: 25126749; PubMed Central PMCID: PMC4134197.
- Inagaki-Ohara K, Mayuzumi H, Kato S, Minokoshi Y, Otsubo T, Kawamura YI, Dohi T, Matsuzaki G, Yoshimura A.
Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice.
Oncogene. 2014 Jan 2;33(1):74-84. doi: 10.1038/onc.2012.540. Epub 2012 Nov 26. PubMed PMID: 23178499.
《2013年》
- Nishimura W, Eto K, Miki A, Goto M, Kawaguchi M, Nammo T, Udagawa H, Hiramoto M, Shimizu Y, Okamura T, Fujiwara T, Yasuda Y, Yasuda K.
Quantitative assessment of Pdx1 promoter activity in vivo using a secreted luciferase reporter system.
Endocrinology. 2013 Nov;154(11):4388-95. doi: 10.1210/en.2012-2248. Epub 2013 Sep 12. PubMed PMID: 24029239.
《2012年》
- Okamura T, Yanobu-Takanashi R, Takeuchi F, Isono M, Akiyama K, Shimizu Y, Goto M, Liang YQ, Yamamoto K, Katsuya T, Fujioka A, Ohnaka K, Takayanagi R, Ogihara T, Yamori Y, Kato N.
Deletion of CDKAL1 affects high-fat diet-induced fat accumulation and glucose-stimulated insulin secretion in mice, indicating relevance to diabetes.
PLoS One. 2012;7(11):e49055. doi: 10.1371/journal.pone.0049055. Epub 2012 Nov 16. PubMed PMID: 23173044; PubMed Central PMCID: PMC3500257.
