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Genome Medical Science
Genome Research
Clinical outcomes of infectious diseases are dependent of the association between the pathogen and the host factors. Several human genome projects are enable us to analyze the genetic or epigenetic factors of individuals.
Our goal of this project is to develop new diagnosis kits and drugs for cure of infectious diseases. Genome data of patients infected with viruses such as hepatitis B, C, E virus, HIV, and HTLV-1 are collected and combined with their clinical and virus sequence data to determine a novel factor associated with clinical outcomes.
- Discovery of viral factors relating with disease onset or progression
- Discovery of host factors relating with disease onset or progression
Hepatitis Research
Our team focus on basic and clinical studies of hepatitis B, and C based on the data of clinical outcomes. Several studies of virological research and disease progression are conducted with collaborators. In clinical, the studies to protect against reactivation of hepatitis B and clinical trials have been in progress.
- Drug development to eliminate HBV completely
- Elucidation of HBV entry-step and the development of new drugs
- Elusidation of HCV replication machinery
- Clinical studies to prevent against reactivation of hepatitis B
International collaborations
We have a lot of collaborators worldwide such as Central Asia, West-East Asia, Central America, and Africa. We have collected both clinical data and patient’s samples in each country. Our data have been referred by these government to make the protocol for the protection from infectious diseases. We provide an opportunity for the training of the experimental techniques to analyze viral and host factors.
- Surveillance of HBV, HCV, and HIV in developing countries
- Development of the protocol for the protection from infectious diseases
- Training of the experimental techniques on young reasercher
Main Staff
| Project Leader | Masashi Mizokami |
|---|---|
| Senior Research Fellow | Uojima Haruki |
| Research Fellows | Tomoko Date |
